Research Studies Prove Packets and Education Increase Opioid Disposal up to 92%

Multiple research studies indicate that providing at-home drug disposal packets, educational materials, and offering counseling can result in the disposal of up to 92% of leftover opioid prescriptions.

While some studies distributed the disposal packets with a prescription at the pharmacy’s point of service, some prescriptions were distributed with activated carbon disposal bags, but the highest rates of proper disposal were achieved by mailing DisposeRx drug disposal packets to the patient a few days after surgery.

Research Studies Prove Packets and Education Increase Opioid Disposal up to 92%

Multiple research studies indicate that providing at-home drug disposal packets, educational materials, and offering counseling can result in the disposal of up to 92% of leftover opioid prescriptions.

While some studies distributed the disposal packets with a prescription at the pharmacy’s point of service, some prescriptions were distributed with activated carbon disposal bags, but the highest rates of proper disposal were achieved by mailing DisposeRx drug disposal packets to the patient a few days after surgery.

Journal of the American Medical Association

Journal of the
American Medical Association

At-home Disposal Kits Increase Proper Opioid Disposal

At the Perelman School of Medicine at the University of Pennsylvania, Lead Researcher Anish K. Agarwal, MD, MPH, saw that after surgery, many patients kept leftover medications in the home increasing the risk of drug addiction and abuse. Agarwal wanted to find whether sending patients a disposal kit could prompt them to properly dispose of the unneeded opioids. His team sent $2 kits to over 200 patients and found that 62% more patients reported they properly disposed of their medications taking almost 500 unused tables off the streets.

Mailing medication disposal kits to patients increased safe opioid disposal by an average of 62%.

Key Data Findings

+
Average age of participants
x
More participants disposed of medications with DisposeRx compared to those that received a text message to drug drop box locations
%
Increase in proper disposal1

Read the Research study on JAMA Network Open, “Effect of Mailing an At-home Disposal Kit on Unused Opioid Disposal After Surgery – A Randomized Clinical Trial


Journal of the Pediatric Orthopaedic Society of North America

Journal of the
Pediatric Orthopaedic Society
of North America

Distributing Packets and Education Boost Medication Disposal

As part of an Opioid Stewardship Initiative, researchers at the Shriners for Children Medical Center in Pasadena, CA wanted to find if giving medication disposal kits with prescriptions could reduce unused medications in the home. Researchers gave DisposeRx packets, an instructional flyer, and offered counseling to opioid prescription recipients and then followed up by phone. As a result, 92% of the participants reported using the provided DisposeRx to dispose of leftover medications.

Providing patients with packets, education materials, and awareness boosts medication disposal to a 92% disposal rate.

Key Data Findings

Encounters
%
338 disposed of medications
%
328 disposed of medications with DisposeRx

Read the Research study in the Journal of the Pediatric Orthopaedic Society of North America, “Preventing Opioid Diversion and Abuse by Using an At-home Opioid Disposal Method: An Improvement Project in a Pediatric Outpatient Surgical Center



Journal of Nursing Administration

Packets, Follow-ups, and Instructional Materials Increase Disposal Up to 71%

Researcher John M. Edwards III, DNAP, CRNA surveyed almost 300 articles about opioid and medical waste disposal and found 8 to be applicable for his review. Of those, Edwards found all eight research studies indicate in-home opioid disposal systems provided by a healthcare facility produce proper medication disposal rates up to 71%.

Key Data Findings

%
Disposal rate using
Educational Flyer and
DisposeRx4

Studies indicate DisposeRx with patient education is most effective at increasing at-home prescription drug disposal

%
Disposal rate using
Educational Flyer and
DisposeRx4

Studies indicate DisposeRx with patient education is most effective at increasing at-home prescription drug disposal

%
Disposal rate with
Handout and Activated
Charcoal bag5
%
Disposal rate with Handout and Activated Charcoal bag6
%
Disposal rate with no education or disposal kit7
%
Disposal rate using education and mail-back envelopes8
%
Disposal rate with
Handout and Activated
Charcoal bag5
%
Disposal rate with Handout
and Activated
Charcoal bag6
%
Disposal rate with no
education or
disposal kit7
%
Disposal rate using education
and mail-back
envelopes8

Read the Research study Surgical Patient Compliance with Healthcare Facility-Provided In-home Opioid Disposal Products: A Systematic Review.


  1. Compared to control group.
  2. Includes cost of postage, flyer and packet.
  3. Kit included flyer and packet.
  4. Zhang DA, Luong M, Barragan E, Bushnell F, Cho R, Poon S. Disposal of unused opioids using an at-home disposal method. J Pediatr Soc North Am. 2021;3(1).
  5. Brummett CM, Steiger R, Englesbe M, et al. Effect of an activated charcoal bag on disposal of unused opioids after an outpatient surgical procedure: a randomized clinical trial. JAMA Surg. 2019;154(6):558-561.
  6. Hite M, Dippre A, Heldreth A, et al. A multifaceted approach to opioid education, prescribing, and disposal for patients with breast cancer undergoing surgery. J Surg Res (Houst). 2021;257:597-604.v
  7. Voepel-Lewis T, Farley FA, Grant J, et al. Behavioral Intervention and Disposal of Leftover Opioids: A Randomized Trial. Pediatrics. 2020;145(1):e20191431.
  8. AdlerAC, Yamani AN, Sutton CD, Guffey DM, Chandrakantan A. Mail-back envelopes for retrieval of opioids after pediatric surgery. Pediatrics. 2020;145(3):e20192449.

DisposeRx encourages evidence based programs that make a difference

DisposeRx currently offers evidence-based turn-key solutions for opioid abatement programs across the country. Programs like Friday Night Lights Against Opioids in Texas and Pharmacy reimbursement programs in Iowa, and offer states an effective prevention method often covered by State Opioid Response Grants (SOR).

If you have an idea for a research study that can help reduce adverse medication events and improve family safety, please reach out today.

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